You need a weapon or technology whose trigger is intention itself, making containment impossible and every holder a potential detonator; or a distributed-threat scenario where the danger is cognitive, not mechanical.

Pyr E is the ultimate uncontrollable weapon: detonated by directed thought alone, with no key, no formula, no physical trigger. "Only Will and Idea are necessary." Bester's distributed-responsibility horror is that the weapon cannot be locked up because the lock would have to be inside every human skull. Once the substance is scattered across Earth, anyone's hatred becomes a detonation sequence. Knowledge, intent, and contamination are inseparable.