MD thesis — Baba Farid University of Health Sciences (Faridkot), 2023. Full text: https://archive.org/details/sgng.17194-to-study-the-clinical-and-etiological-profile-of-epileptic-spasms
Epileptic spasms cause severe developmental regression (73.2% of cases here) — and the leading causes are preventable perinatal injuries, not medical mysteries.
In this North Indian cohort, epileptic spasms are overwhelmingly a perinatal-injury disease — 80.5% of 41 cases traced to perinatal illness, with perinatal asphyxia the lead cause and neonatal hypoglycemic brain injury an under-recognized driver tied to low birth weight, suboptimal neonatal care, and reluctance to use alternative feeds.
Why it matters
Epileptic spasms cause severe developmental regression (73.2% of cases here) — and the leading causes are preventable perinatal injuries, not medical mysteries.
Use when: When the cause is preventable, the study is an indictment — four in five cases traced to perinatal injury means the intervention point is the delivery room, not the neurology ward.
