"In 1736 I lost one of my sons, a fine boy of four years old, by the small-pox, taken in the common way. I long regretted bitterly, and still regret that I had not given it to him by inoculation." "my example showing that the regret may be the same either way, and that, therefore, the safer should be chosen."

— In our words · Source: The Autobiography of Benjamin Franklin (Benjamin Franklin)